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dc.contributor.authorCosta, Guilherme Jorge-
dc.contributor.authorAzevedo, Carla Rameri Alexandre Silva de-
dc.contributor.authorCosta Júnior, José Iran-
dc.contributor.authorBergmann, Anke-
dc.contributor.authorThuler, Luiz Claudio Santos-
dc.date.accessioned2022-06-10T15:36:45Z-
dc.date.available2022-06-10T15:36:45Z-
dc.date.issued2021-
dc.identifier.urihttp://higia.imip.org.br/handle/123456789/727-
dc.description.abstractBackground: Coronavirus disease 2019 (COVID-19) and cancer are serious public health problems worldwide. However, little is known about the risk factors of in-hospital mortality among COVID-19 patients with and without cancer in Brazil. The objective of this study was to evaluate the risk factors of in-hospital mortality among COVID-19 patients with and without cancer and to compare mortality according to gender and topography during the year 2020 in Brazil. Methods: This was a secondary data study of hospitalized adult patients with a diagnosis of COVID-19 by real-time polymerase chain reaction testing in Brazil. The data were collected from the Influenza Epidemiological Surveillance Information System. Results: This study analyzed data from 322,817 patients. The prevalence of cancer in patients with COVID-19 was 2.3%. COVID-19 patients with neurological diseases and cancer had the most lethal comorbidities in both sexes. COVID-19 patients with cancer were more likely to be older (median age, 67 vs 62 years; P < .001), to have a longer hospital stay (13.1 vs 11.5 days; P < .001), to be admitted to the intensive care unit (45.3% vs 39.6%; P < .001), to receive more invasive mechanical ventilation (27.1% vs 21.9%), and to have a higher risk of death (adjusted odds ratio [aOR], 1.94; 95% confidence interval [CI], 1.83-2.06; P < .001) than those without cancer. Patients with hematological neoplasia (aOR, 2.85; 95% CI, 2.41-3.38; P < .001) had a higher risk of mortality than those with solid tumors (aOR, 1.83; 95% CI, 1.72-1.95; P < .001) in both sexes. Conclusions: Brazilian COVID-19 patients with cancer have higher disease severity and a higher risk of mortality than those without cancer.pt_BR
dc.language.isoenpt_BR
dc.subjectNeoplasiaspt_BR
dc.subjectCOVID-19pt_BR
dc.subjectFatores de riscopt_BR
dc.titleHigher severity and risk of in-hospital mortality for COVID-19 patients with cancer during the year 2020 in Brazil: A countrywide analysis of secondary datapt_BR
dc.higia.programArtigos científicos colaboradores IMIPpt_BR
dc.higia.tipoArtigo Científicopt_BR
dc.higia.pages9 p.pt_BR
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