Use este identificador para citar ou linkar para este item: http://higia.imip.org.br/handle/123456789/749
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dc.contributor.authorHolanda, Narriane Chaves Pereira de-
dc.contributor.authorBaad, Vanessa Mayana Alves-
dc.contributor.authorBezerra, Luísa Rayra-
dc.contributor.authorLima, Silvane Katarine Medeiros de-
dc.contributor.authorFilho, João Modesto-
dc.contributor.authorLimeira, Caio Chaves de Holanda-
dc.contributor.authorCavalcante, Taisy Cinthia Ferro-
dc.contributor.authorMontenegro, Ana Carla Peres-
dc.contributor.authorBandeira, Francisco-
dc.date.accessioned2022-06-16T14:19:37Z-
dc.date.available2022-06-16T14:19:37Z-
dc.date.issued2021-
dc.identifier.urihttp://higia.imip.org.br/handle/123456789/749-
dc.description.abstractMaterials and Methods: In this cross-sectional study, we compared the prevalence of secondary hyperparathyroidism (SHPT), impact on bone mass and turnover markers, and serum leptin after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in 117 patients (91% female, 51% RYGB, age 41.8 ± 6.7 years, time of surgery 4.3 ± 3.4 years) at different times (1–2 years, > 2 and < 5 years and ≥ 5 years). Body composition, bone mineral density (BMD), by dual-energy X-ray absorptiometry, and bone parameters (PTH, serum calcium, 25OHD, alkaline phosphatase (AP), C-telopeptide (CTX)) were analyzed. Results: Prevalence of SHPT (PTH ≥ 65 pg/ml) was 26%, RYGB > SG (18.4% vs. 7.8%, p = 0.039), despite similar 25OHD and calcium levels. Mean PTH, CTX, and AP were higher in RYGB vs. SG (61.3 ± 29.5 vs 49.5 ± 32.3 pg/ml, p = 0.001; 0.596 ± 0.24 vs. 0.463 ± 0.23 ng/ml; 123.9 ± 60.8 vs. 100.7 ± 62.0 U/l). There were 13.5% decreases in femoral neck BMD in all patients, over the study period. In the last group, the RYGB group showed greater bone loss in total body BMD (1.016 vs. 1.151 g/cm2, − 8.1%, p = 0.003) and total femur BMD (1.164 vs. 1.267 g/cm2, − 11.7%, p = 0.007). Mean leptin was lower in the RYGB vs. SG group, with no correlation with BMD in any site. Conclusion: Our data suggest a more deleterious role of RYGB on bone remodeling up to 5 years postoperatively in comparison with SG.pt_BR
dc.language.isoenpt_BR
dc.subjectHiperparatireoidismo secundáriopt_BR
dc.subjectCirurgia bariátricapt_BR
dc.subjectGastrectomiapt_BR
dc.titleSecondary hyperparathyroidism, bone density, and bone turnover after bariatric surgery: differences between roux-en-y gastric bypass and sleeve gastrectomypt_BR
dc.higia.programArtigos científicos colaboradores IMIPpt_BR
dc.higia.tipoArtigo Científicopt_BR
dc.higia.pages9 p.pt_BR
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