Use este identificador para citar ou linkar para este item: http://higia.imip.org.br/handle/123456789/897
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dc.contributor.authorMazur, Natalie I.-
dc.contributor.authorLöwensteyn, Yvette N.-
dc.contributor.authorWillemsen, Joukje E.-
dc.contributor.authorGill, Christopher J.-
dc.contributor.authorForman, Leah-
dc.contributor.authorMwananyanda, Lawrence M.-
dc.contributor.authorBlau, Dianna M.-
dc.contributor.authorBreiman, Robert F.-
dc.contributor.authorMadhi, Shabir A.-
dc.contributor.authorMahtab, Sana-
dc.contributor.authorGurley, Emily S.-
dc.contributor.authorArifeen, Shams E. l.-
dc.contributor.authorAssefa, Nega-
dc.contributor.authorScott, J Anthony G.-
dc.contributor.authorOnyango, Dickens-
dc.contributor.authorBarr, Beth A.Tippet-
dc.contributor.authorKotloff, Karen L.-
dc.contributor.authorSow, Samba O.-
dc.contributor.authorMandomando, Inacio-
dc.contributor.authorOgbuanu, Ikechukwu-
dc.contributor.authorJambai, Amara-
dc.contributor.authorBassat, Quique-
dc.contributor.authorCHAMPS Network the RSV GOLD Study Group [‪Bezerra, ‪Patrícia Gomes de Matos-
dc.contributor.authorDuarte, Maria do Carmo Menezes Bezerra]-
dc.contributor.authorCaballero, Mauricio T-
dc.contributor.authorPolack, Fernando P.-
dc.contributor.authorOmer, Saad-
dc.contributor.authorKazi, Abdul Momin-
dc.contributor.authorSimões, Eric A. F.-
dc.contributor.authorSatav, Ashish-
dc.contributor.authorBont, Louis J-
dc.date.accessioned2022-07-14T16:53:11Z-
dc.date.available2022-07-14T16:53:11Z-
dc.date.issued2021-
dc.identifier.urihttp://higia.imip.org.br/handle/123456789/897-
dc.description.abstractBackground: Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% of mortality occurring in low- and lower middle-income countries. At least half of RSV-related deaths are estimated to occur in the community, but clinical characteristics of this group of children remain poorly characterized. Methods: The RSV Global Online Mortality Database (RSV GOLD), a global registry of under-5 children who have died with RSV-related illness, describes clinical characteristics of children dying of RSV through global data sharing. RSV GOLD acts as a collaborative platform for global deaths, including community mortality studies described in this supplement. We aimed to compare the age distribution of infant deaths <6 months occurring in the community with in-hospital. Results: We studied 829 RSV-related deaths <1 year of age from 38 developing countries, including 166 community deaths from 12 countries. There were 629 deaths that occurred <6 months, of which 156 (25%) occurred in the community. Among infants who died before 6 months of age, median age at death in the community (1.5 months; IQR: 0.8-3.3) was lower than in-hospital (2.4 months; IQR: 1.5-4.0; P < .0001). The proportion of neonatal deaths was higher in the community (29%, 46/156) than in-hospital (12%, 57/473, P < 0.0001). Conclusions: We observed that children in the community die at a younger age. We expect that maternal vaccination or immunoprophylaxis against RSV will have a larger impact on RSV-related mortality in the community than in-hospital. This case series of RSV-related community deaths, made possible through global data sharing, allowed us to assess the potential impact of future RSV vaccines.pt_BR
dc.language.isoenpt_BR
dc.subjectDoenças respiratóriaspt_BR
dc.subjectCriançaspt_BR
dc.subjectMortalidadept_BR
dc.titleGlobal respiratory syncytial virus-related infant community deathspt_BR
dc.higia.programArtigos científicos colaboradores IMIPpt_BR
dc.higia.tipoArtigo Científicopt_BR
dc.higia.pages9 p.pt_BR
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